Buddenbrooks by Thomas Mann

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Cases of typhoid fever take the following course.

The patient feels depressed and moody -- a condition which grows rapidly worse until it amounts to acute despondency. At the same time he is overpowered by physical weariness, not only of the muscles and sinews, but also of the organic functions, in particular of the digestion -- so that the stomach refuses food. There is a great desire for sleep, but even in conditions of extreme fatigue the sleep is restless and superficial and not refreshing. There is pain in the head, the brain feels dull and confused, and there are spells of giddiness. An indefinite ache is felt in all the bones. There is blood from the nose now and then, without apparent cause.

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