Arrowsmith by Sinclair Lewis

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The driver of the wagon swaying through forest and swamp of the Ohio wilderness was a ragged girl of fourteen. Her mother they had buried near the Monongahela-the girl herself had heaped with torn sods the grave beside the river of the beautiful name. Her father lay shrinking with fever on the floor of the wagon-box, and about him played her brothers and sisters, dirty brats, tattered brats, hilarious brats.

She halted at the fork in the grassy road, and the sick man quavered, "Emmy, ye better turn down towards Cincinnati. If we could find your Uncle Ed, I guess he'd take us in."

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