Arrowsmith by Sinclair Lewis

Aware only of Madeline Fox and Orchid Pickerbaugh, who were Nice American Girls, of soon-forgotten ladies of the night, and of Leora, who, in her indolence, her indifference to decoration and good fame, was neither woman nor wife but only her own self, Martin knew nothing whatever about Women. He had expected Leora to wait for him, to obey his wishes, to understand without his saying them all the flattering things he had planned to say. He was spoiled, and Joyce was not timorous about telling him so.

It was not for her to sit beaming and wordless while he and his fellow-researchers arranged the world. With many jolts he perceived that even outside the bedroom he had to consider the fluctuations and variables of his wife, as A Woman, and sometimes as A Rich Woman.